Barium oxalate succinate

Barium oxalate succinate

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Basics

Alpha-ketoglutaric acid is an essential building block in the citrate cycle and nitrogen transport. It is a dicarboxylic acid and a derivative of n-pentane. It is usually present in the form of colorless and odorless crystals. From a pharmaceutical point of view, alpha-ketoglutaric acid is not yet used as a drug - except in homeopathic remedies. However, it is already the subject of intensive research and is said to help with metabolic disorders and obesity, among other things. Recent studies have demonstrated a muscle protein-building effect that can help patients rebuild muscle after surgery.

Graphic structural formula of the active ingredient alpha-ketoglutaric acid

Effect

Alpha-ketoglutaric acid is an intermediate in the citrate cycle and is converted into succinyl coenzyme A by a dehydrogenase. As a nitrogen transporter, amino groups of amino acids can be attached to the respective molecule and thus transported to the liver, where they then act in the urea cycle.

Dosage

Always take alpha-ketoglutaric acid exactly as described in the package leaflet or as advised by your doctor.

Adults:

The usual recommended dose is 22 mg 1-3 times a week.

The recommended dose for acute symptoms is 22 mg daily for 3 days .

Alpha-ketoglutaric acid is used intramuscularly (application into the muscle), subcutaneously (application under the skin) or intradermally (application into the skin).

Children & adolescents:

The usual recommended dose is 22 mg 1-3 times a week.

The recommended dose for acute symptoms is 22 mg daily for 3 days .

Alpha-ketoglutaric acid is used intramuscularly (application into the muscle), subcutaneously (application under the skin) or intradermally (application into the skin).

Side Effects

The following side effects may occur:

  • Allergic reactions
  • Hypersensitivity reactions

Interactions

There are no known interactions, as no studies have been carried out.

Contraindications

Alpha-ketoglutaric acid must NOT be taken in the following cases:

  • In case of allergy to alpha-ketoglutaric acid

Age Restriction

Alpha-ketoglutaric acid can be used from the age of 12.

Pregnancy & Lactation

Alpha-ketoglutaric acid can be used during pregnancy and breastfeeding after consultation with your doctor.

Chemical & physical properties

Formula C5H6O5
Molar Mass (g·mol−1) 146,098
Physical State solid
Density (g·cm−3) 1,5
Melting Point (°C) 113-118
Boiling Point (°C) 323
PKS Value 2,66
CAS Number 328-50-7
PUB Number 51
Drugbank ID DB08845

Sources

Editorial principles

All information used for the content comes from verified sources (recognised institutions, experts, studies by renowned universities). We attach great importance to the qualification of the authors and the scientific background of the information. Thus, we ensure that our research is based on scientific findings.
Thomas Hofko

Thomas Hofko
Author

Thomas Hofko is in the final third of his bachelor's degree in pharmacy and is an author and lecturer on pharmaceutical topics. He is particularly interested in the fields of clinical pharmacy and phytopharmacy.

The content of this page is an automated and high-quality translation from DeepL. You can find the original content in German here.

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The contents shown do not replace the original package insert of the medicinal product, especially with regard to dosage and effect of the individual products. We cannot assume any liability for the correctness of the data, as the data was partly converted automatically. A doctor should always be consulted for diagnoses and other health questions. Further information on this topic can be found here.